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MIGRA
MIGRA

Therapeutic Category
Migraine medicine
Pharmaceutical Form
Tablets

Composition Each tablet contains: Paracetamol 500 mg + Metoclopramide Hcl 5 mg.
Properties & Indications Anovel synergistic action is obtained by combination of Paracetamol & Metoclopramide.
So Migra becomes highly effective in treating the syndromes associated with pain and nausea – as with Migraine attacks, in addition to the antemetic action, and the associated nausea.
It,s effect is proved also in the treatment of vomiting manifested with hyperthermia in particular, as in cases of G.l infections
Contra Indications - Is not recommended for patients with hepatic or renal impairment.
- Is not given post surgery, neither for patients with intestinal obstruction ,nor with digestive hemorrhage
Side Effects Mostly no undesired effects is noticed with the recommended doses, but :
- Extrapyramidal symptoms may occur due to high dose of Metoclopramide.
- Drowsiness, Lassitude, Skin rash occur rarely, but no longer if treatment is stopped.
Precautions When necessary with pregnancy or during lactation , the drug shall be given with caution.
Drug Interactions Such interactions occur with :
- Antimuscarinic Drugs antagonize the effect of Metoclopramide.
- Neurological inhibitors may increase the product effects.
- Alcohol toxicity is increased with the drug.
- Desipramine reduces the absorption of the drug.
- With Other analgesic products:
- With Phenobarbitones, as its tolerance is increased
- With Asperin : as the salicylates concentration is increased in blood.
Use & Dose By oral administration:
Adults : 1-2 tablets 3-4 times daily , or according to physicians directions.
Over Dosage With high doses and during the first 24 hours, there might be Lassitude, Fatigue, Vomiting, Loss of appetite and Abdominal Pain, if high doses are taken.
Liver necrosis might occur too, due to paracetamol.
Packing 20 tablets in two blisters in a blue cartoon pack with insert leaflet.